Research Article

Effect of Polyherbal Mixtures on the Treatment of Diabetes

Table 4

Effect of mixtures on body weight of STZ-induced diabetic rat.

GroupsInitial weight (gm)Final weight (gm)Change in body weightChange in body weight (%)

Normal control210.00 ± 8.91255.17 ± 67845.17 ± 6.78
Diabetic control231.17 ± 8.78212.00 ± 8.42
Diabetic + glibenclamide218.00 ± 7.89**256.50 ± 8.16**38.50 ± 5.98** +22.65 ± 1.08**
Diabetic + mixture 1200.84 ± 7.75*222.49 ± 6.78*21.65 ± 8.9* +12.45 ± 2.96*
Diabetic + mixture 2220.13 ± 8.75*243.91 ± 5.67*23.78 ± 5.81* +12.50 ± 3.86*
Diabetic + mixture 3200.17 ± 7.45**226.35 ± 6.02**26.18 ± 6.21** +14.37 ± 1.96**
Diabetic + mixture 4205.83 ± 7.33*221.48 ± 7.66*15.65 ± 8.88* +9.10 ± 1.23*
Diabetic + mixture 5208.87 ± 7.75*229.52 ± 7.88*20.65 ± 5.83* +11.54 ± 1.05*

Results expressed as mean ± SD ( ). Treatment was done for 21 days. The data were statistically analysed by one-way ANOVA, followed by Dunnett’s -test. , . values less than 0.01 were considered more significant.