Research Article

Development and Validation of a Simple and Sensitive Spectrometric Method for Estimation of Cisplatin Hydrochloride in Tablet Dosage Forms: Application to Dissolution Studies

Table 1

Stability of the cisplatin hydrochloride stock standard solution at a concentration of 0.8  g/mL in mixture of 1.4 mg/mL of OPDA solution, phosphate buffer pH 6.8, and DMF.

0 h1 h5 h12 h24 h1 weekMeanR.S.D.%

Responses at 706 nm0.1760.1780.1700.1790.1750.1750.1751.79
0.1780.1770.1750.1780.1760.1720.1761.30
0.1740.1750.1720.1760.1720.1700.1731.29