NT-proBNP Changes in Patients with Ascites during Large Volume Paracentesis

Table 2

Clinical correlations with significant serum NT-proBNP changes at both time points.

2L prealbumin		End of drainage
Clinical parameter	𝑃 value	Clinical parameter	𝑃 value
Age	0.06	Age	0.12
Gender	0.98	Gender	0.98
Child-Pugh score	0.38	Child-Pugh score	0.84
MELD	0.06	MELD	0.05
Cause of cirrhosis:		Cause of cirrhosis:
Alcohol versus nonalcohol	0.13	Alcohol versus nonalcohol	0.41
History of		History of
Varices	0.18	Varices	0.37
Previous SBP	0.83	Previous SBP	0.89
Previous HE	0.80	Previous HE	0.57
HCC	0.68	HCC	0.87
Comorbid:		Comorbid:
CCF	0.12	CCF	0.04
CRF	0.35	CRF	0.36
HT	0.87	HT	0.66
Diuretics	0.62	Diuretics	0.11
Serum Na	0.84	Serum Na	0.83
Serum creatinine	0.21	Serum creatinine	0.43
eGFR	0.22	eGFR	0.46
Serum bilirubin	0.60	Serum bilirubin	0.24
Serum albumin	0.32	Serum albumin	0.93
ALT	0.58	ALT	0.44
AST	0.78	AST	0.77
GGT	0.04	GGT	0.34
ALP	0.10	ALP	0.15
Haemoglobin	0.58	Haemoglobin	0.78
White cell count	0.07	White cell count	0.26
Platelets	0.13	Platelets	0.31
INR	0.12	INR	0.23
SAAG	0.05	SAAG	0.72
Ascitic protein	0.48	Ascitic protein	0.66
Ascitic albumin	0.47	Ascitic albumin	0.83
Baseline heart rate	0.56	Baseline heart rate	0.47
Baseline systolic BP	0.59	Baseline systolic BP	0.93
Baseline diastolic BP	0.59	Baseline diastolic BP	0.81
Total volume drained	0.79	Total volume drained	0.49
Baseline NT-proBNP	<0.01	Baseline NT-proBNP	0.01

MELD: model for end-stage liver disease; HCC: hepatocellular carcinoma; CCF: congestive cardiac failure; CRF: chronic renal failure; HT: hypertension; Na: sodium; eGFR: estimated glomerular filtration rate; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma glutamate transferase; ALP: alkaline phosphatase; INR: international normalised ratio; SAAG: serum ascites albumin gradient.