Research Article

Antioxidant and Antidiabetic Effect of Aqueous Fruit Extract of Passiflora ligularis Juss. on Streptozotocin Induced Diabetic Rats

Table 2

Effect of P.ligularis on glucose, hemoglobin, glycosylated hemoglobin, and lipid profile in serum of control and experimental rats.

ParametersGlucose (mg/dL)Hemoglobin (mg/dL)Glycosylated hemoglobin (%)Total cholesterol (mg/dL)Triglycerides (mg/dL)HDL (mg/dL)

Control  
(Group I)
96.1 ± 0.28a13.3 ± 0.43a6.5 ± 0.12a111.6 ± 5.77 a77.4 ± 0.40a21.3 ± 0.28a
Diabetic control  
(Group II)
221.6 ± 2.28b6.8 ± 0.05b11.2 ± 0.01b228.3 ± 2.88b188.5 ± 0.46b15.2 ± 0.21b
Diabetes + glibenclamide  
(Group III)
111.6 ± 0.57c13.3 ± 0.04a5.4 ± 0.04c115.6 ± 1.15a101.6 ± 2.88c23.0 ± 0.04c
Diabetes + P. ligularis extract  
(Group IV)
116.1 ± 0.28d12.7 ± 0.12c6.3 ± 0.05d131.6 ± 2.88c88.8 ± 0.11d25.1 ± 0.28d
P. ligularis extract treated alone  
(Group V)
95.1 ± 0.28a13.4 ± 0.01a6.6 ± 0.02a101.6 ± 2.88d78.8 ± 0.28a21.3 ± 0.28a

Values are expressed as mean ± SD for four animals in each group.
Values not sharing common superscript letters (a–d) differ significantly at (DMRT).