Antioxidant and Antidiabetic Effect of Aqueous Fruit Extract of Passiflora ligularis Juss. on Streptozotocin Induced Diabetic Rats

Table 3

Effect of P. ligularis on kidney and liver markers, total protein, albumin, and globulin in serum of control and experimental rats.

Parameters	Urea (mg/dL)	Creatinine (mg/dL)	Bilirubin (mg/dL)	SGOT (IU/L)	SGPT (IU/L)	Total protein (mg/dL)	Albumin (mg/dL)	Globulin (mg/dL)
Control; (Group I)	27.9 ± 0.01^a	0.5 ± 0.06^a	1.10 ± 0.01^a	33.3 ± 0.28^a	27.4 ± 0.40^a	8.2 ± 0.23^a	5.5 ± 0.11^a	2.4 ± 0.67^a
Diabetic control   (Group II)	30.4 ± 0.46^b	0.7 ± 0.04^b	1.33 ± 0.02^b	56.1 ± 0.98^b	59.0 ± 0.80^b	4.6 ± 0.02^b	3.3 ± 0.02^b	0.6 ± 0.01^b
Diabetes + glibenclamide  (Group III)	25.4 ± 0.34^c	0.5 ± 0.01^a	1.18 ± 0.01^c	38.4 ± 0.40^c	33.3 ± 0.23^c	7.7 ± 0.03^c	4.8 ± 0.26^c	2.9 ± 0.05^c
Diabetes + P. ligularis extract  (Group IV)	23.2 ± 0.35^d	0.4 ± 0.01^c	1.15 ± 0.01^d	43.3 ± 0.28^d	41.0 ± 0.86^d	7.2 ± 0.08^d	4.7 ± 0.19^c	2.3 ± 0.06^a
P. ligularis extract treated alone  (Group V)	27.6 ± 0.34^a	0.6 ± 0.01^d	1.09 ± 0.01^a	35.1 ± 0.28^e	29.3 ± 0.28^e	8.6 ± 0.05^e	5.4 ± 0.10^a	3.1 ± 0.01^d

Values are expressed as mean ± SD for four animals in each group.
Values not sharing common superscript letters (a–d) differ significantly at (DMRT).