Antioxidant and Antidiabetic Effect of Aqueous Fruit Extract of Passiflora ligularis Juss. on Streptozotocin Induced Diabetic Rats
Table 5
Activity of aqueous fruit extract of Passiflora ligularis on the antioxidant enzymes in the liver, kidney, and pancreas of control and experimental rats.
Particulars
Superoxide dismutase (enzyme required for 50% inhibition of NBT reduction/min/mg protein)
Catalase (µmoles of H2O2utilized/min/mg/protein)
Glutathione peroxidase (µmoles of GSH utilized/min/mg/protein)
Liver
Kidney
Pancreas
Liver
Kidney
Pancreas
Liver
Kidney
Pancreas
Control (Group I)
6.71 ± 0.01a
2.13 ± 0.03a
1.13 ± 0.01a
2.04 ± 0.10a
2.04 ± 0.10a
2.2 ± 0.13a
1.04 ± 0.25a
1.36 ± 0.3a
1.77 ± 0.06a
Diabetic control (Group II)
3.93 ± 0.02b
0.94 ± 0.03b
0.63 ± 0.01b
0.8 ± 0.05b
0.8 ± 0.05b
0.93 ± 0.13b
0.52 ± 0.17b
0.72 ± 0.2b
1.15 ± 0.08b
Diabetic+ glibenclamide (Group III)
6.4 ± 0.2c
1.93 ± 0.02c
0.93 ± 0.02c
1.1 ± 0.31c
1.18 ± 0.31c
1.27 ± 0.51c
0.93 ± 0.18c
0.78 ± 0.09b
1.45 ± 0.2c
Diabetic + Passiflora ligularis (Group IV)
5.91 ± 0.01d
1.76 ± 0.02d
0.88 ± 0.01d
1.68 ± 0.11d
1.68 ± 0.11d
1.84 ± 0.41d
0.84 ± 0.05d
1.12 ± 0.14c
1.6 ± 0.06d
Passiflora ligularis alone treated (Group V)
6.56 ± 0.03ca
1.97 ± 0.01c
1.16 ± 0.03a
1.97 ± 0.13a
1.97 ± 0.13ad
2.16 ± 0.16a
1.04 ± 0.2a
1.53 ± 0.19d
1.72 ± 0.08a
Values are expressed as mean ± SD for four animals in each group. Values not sharing common superscript letters (a–d) differ significantly at (DMRT).