Research Article

Antioxidant and Antidiabetic Effect of Aqueous Fruit Extract of Passiflora ligularis Juss. on Streptozotocin Induced Diabetic Rats

Table 5

Activity of aqueous fruit extract of Passiflora ligularis on the antioxidant enzymes in the liver, kidney, and pancreas of control and experimental rats.

Particulars Superoxide dismutase  
(enzyme required for 50% inhibition of NBT reduction/min/mg protein)
Catalase  
(µmoles of H2O2utilized/min/mg/protein)
Glutathione peroxidase  
(µmoles of GSH utilized/min/mg/protein)
LiverKidneyPancreasLiverKidneyPancreasLiverKidneyPancreas

Control  
(Group I)
6.71 ± 0.01a2.13 ± 0.03a1.13 ± 0.01a2.04 ± 0.10a2.04 ± 0.10a2.2 ± 0.13a1.04 ± 0.25a1.36 ± 0.3a1.77 ± 0.06a
Diabetic control  
(Group II)
3.93 ± 0.02b0.94 ± 0.03b0.63 ± 0.01b0.8 ± 0.05b0.8 ± 0.05b0.93 ± 0.13b0.52 ± 0.17b0.72 ± 0.2b1.15 ± 0.08b
Diabetic+ glibenclamide
(Group III)
6.4 ± 0.2c1.93 ± 0.02c0.93 ± 0.02c1.1 ± 0.31c1.18 ± 0.31c1.27 ± 0.51c0.93 ± 0.18c0.78 ± 0.09b1.45 ± 0.2c
Diabetic + Passiflora ligularis (Group IV)5.91 ± 0.01d1.76 ± 0.02d0.88 ± 0.01d1.68 ± 0.11d1.68 ± 0.11d1.84 ± 0.41d0.84 ± 0.05d1.12 ± 0.14c1.6 ± 0.06d
Passiflora ligularis alone treated  
(Group V)
6.56 ± 0.03ca1.97 ± 0.01c1.16 ± 0.03a1.97 ± 0.13a1.97 ± 0.13ad2.16 ± 0.16a1.04 ± 0.2a1.53 ± 0.19d1.72 ± 0.08a

Values are expressed as mean ± SD for four animals in each group.
Values not sharing common superscript letters (a–d) differ significantly at (DMRT).