Analytical Method Development and Validation of Solifenacin in Pharmaceutical Dosage Forms by RP-HPLC

Table 2

Assay (mg/g)	𝐴Sa  × standard weight × sample dilution × %P × 1000
	𝐴Std  × standard dilution × sample weight × 100
Assay (%)	Assay (mg/g) × 100
	Theoretical weight (mg/g)
Label claim (%)	𝐴Sb  × standard weight × sample dilution × %P × 100
	𝐴Std  × standard dilution ×  𝑁  × 100 × LC

𝐴_Sa: area of sample in blend assay.
𝐴_Sb: area of sample in drug product assay.
𝐴_Std: mean area of standard.
Spl: drug substance sample for assay.
Spt: drug substance standard for assay.
%P: percentage of potency (as is basis).
LC: label claim in mg.