Prenatal Exposure to Lamotrigine: Effects on Postnatal Development and Behaviour in Rat Offspring

Table 2

Effect of LTG on length of gestation, total number of litters, and its viability index.

Group	Treatment	Gestational length (Days)	Total number of litters	Viability index (%)
I	Control	19.33±0.33	10.00±0.58	100.00±0.00
II	LTG (11.5 mg/kg, p.o)	22.25±0.47^∗∗	6.75±1.49	80.20±15.90
III	LTG (23 mg/kg, p.o)	22.00±0.00^∗∗	8.33±0.67	81.48±13.36
IV	LTG (46 mg/kg, p.o)	—	—	—

𝑛=6/group. Values are expressed in mean ± SEM. Significance with Tukey’s test following one way ANOVA is indicated as ^∗𝑃≤0.05 and ^∗∗𝑃≤0.01 versus control group.