Simultaneous Estimation of Ambroxol Hydrochloride and Cetirizine Hydrochloride in Pharmaceutical Tablet Dosage Form by Simultaneous Equation Spectrophotometric Method: A Quality Control Tool for Dissolution Studies

Table 3

Optical characteristics of Ambroxol Hydrochloride and Cetirizine Hydrochloride.

Optical characteristics	Ambroxol Hydrochloride	Cetirizine Hydrochloride
𝜆max. (nm)	244	230
Beer-Lambert’s law limit (µg/mL)	2–18	2–20
Regression equation (𝑦=𝑚𝑥+𝑐)	𝑦=0.025𝑥−0.002	𝑦=0.032𝑥+0.011
Slope (𝑚)	0.025	0.032
Intercept (𝑐)	0.002	0.011
Correlation coefficient (𝑅)	0.999	0.999
LOD (µg/mL)	0.450	0.457
LOQ (µg/mL)	1.424	1.386
Precision (%RSD)
Repeatability	0.452	0.381
Intraday	0.374	0.416
Interday	0.942	0.863