p16 Expression Is Lost in Severely Atypical Cellular Blue Nevi and Melanoma Compared to Conventional, Mildly, and Moderately Atypical Cellular Blue Nevi

Table 4

𝑃 values for comparison between CBN and conventional benign/atypical melanocytic nevi for p16 and Ki-67 staining.

CBN versus; conventional benign/atypical melanocytic nevi; (𝑁=8)	p16 intensity	% melanocytes stained; with p16	% melanocytes stained; with Ki-67
All CBN (𝑁=15)	0.036	0.808	0.318
Benign/mildly atypical CBN (𝑁=6)	0.728	0.248	0.37
Benign/mildly/moderately atypical CBN (𝑁=10)	0.516	0.237	0.45
Moderately atypical CBN (𝑁=4)	0.576	0.474	0.795
Moderately/severely atypical CBN (𝑁=9)	0.022	0.331	0.438
Severely atypical CBN (𝑁=5)	0.009	0.044	0.428