Review Article

Expression and Regulation of Facilitative Glucose Transporters in Equine Insulin-Sensitive Tissue: From Physiology to Pathology

Figure 1

Regulation of glucose transport in striated muscle. GLUT4 translocation to the cell surface is mediated by both insulin-dependent and -independent pathways. GLUT: glucose transporter; PI 3-kinase: phosphatidylinositide 3-kinase; IRS: insulin receptor substrate; Ca2+: calcium; SR: sarcoplasmic reticulum.
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