Primary Synovial Sarcomas of the Mediastinum: A Systematic Review and Pooled Analysis of the Published Literature

Table 1

Characteristics of the forty cases of mediastinal synovial sarcoma reported in the literature.

Variable	Result (range)
Median age	30.5 years (3–83 years)
Male : female ratio	2.9 : 1
Median size	11 cm (5–20 cm)
Status at presentation
Localized resectable	22 (55%)
Locally advanced, unresectable	16 (40%)
Metastatic	2 (5%)
Location
Anterior/middle mediastinum	28 (70%)
Posterior mediastinum	8 (20%)
Uncertain	4 (10%)
Histologic subtype
Monophasic	18 (45%)
Biphasic	13 (33%)
Uncertain	9 (22%)
Surgical resection
Complete resection	23 (58%)
No resection or partial resection	17 (42%)
Presenting symptoms and signs*
Chest or shoulder pain	22/32 (69%)
Shortness of breath	20/32 (63 %)
Cough	5/32 (16%)
Pericardial effusion	7/32 (22%)
Pleural effusion	3/32 (9%)
Weakness and fatigue	4/32 (13%)
Fever	4/32 (13%)
Weight loss	3/32 (9%)
SVC obstruction	1/32 (3%)

SVC: superior vena cava.
∗32 patients had clear data about clinical presentation.