Intravesical Liposome and Antisense Treatment for Detrusor Overactivity and Interstitial Cystitis/Painful Bladder Syndrome
Figure 3
Scheme for formulation of BoNT into liposomes for bladder instillation. Freeze dried BoNT is resuspended in distilled water and added to vials containing a desiccated liposomal preparation made of phospholipids. This reconstituted suspension is allowed to hydrate at room temperature for 30–60 min before instillation.