Research Article
Study of the Effect of Dillenia indica Fruit Mucilage on the Properties of Metformin Hydrochloride Loaded Spray Dried Microspheres
Table 1
It contains the composition and formulation parameters of metformin HCl loaded microspheres using mucilage of D. indica by spray drying method.
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Formulation codes | Composition and formulation parameters | Mucilage of DI (%) | Inlet temp. (°C) | Outlet temp. (°C) | Feed flow rate (mL·min−1) | Aspirator flow rate (Nm3·mL−1) | Constant parameters |
| SD1 | 1 | 160 | 110 | 1.5 | 26 | Metformin HCl (%) = 1.5; nozzle size (mm) = 0.7; pump speed (rpm) = 2.0; water (mL) = 200 | SD2 | 2 | 160 | 110 | 1.5 | 26 | SD3 | 3 | 160 | 110 | 1.5 | 26 | SD4 | 1 | 170 | 115 | 1.7 | 27 | SD5 | 2 | 170 | 115 | 1.7 | 27 | SD6 | 3 | 170 | 115 | 1.7 | 27 | SD7 | 1 | 175 | 120 | 1.8 | 28 | SD8 | 2 | 175 | 120 | 1.8 | 28 | SD9 | 3 | 175 | 120 | 1.8 | 28 | SD10 | 1 | 180 | 130 | 1.9 | 29 | SD11 | 2 | 180 | 130 | 1.9 | 29 | SD12 | 3 | 180 | 130 | 1.9 | 29 |
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