Review Article

Effects of Commercially Available Dietary Supplements on Resting Energy Expenditure: A Brief Report

Table 1

Investigations evaluating the effects of thermogenic products on resting energy expenditure (REE) following acute (24 hours or less) and extended (longer than 24 hours).

SubjectsIngredientsFindingsAuthor

Effects of acute consumption of dietary supplements on energy expenditure

Obese men ( )Green tea extract 750 mg L-tyrosine 609 mg caffeine 151 mg cayenne 225 mg calcium 1965 mgSupplement containing bioactive food ingredients increased daily REE by 200 kJ or 2% (48 kcal)Belza and Jessen 2005 [34]

Healthy men and women ( )Caffeine anhydrous toothed clubmoss (Huperzia serrata) yerba mate (Llex paraguariensis) 3′-5′-CAMP (3′-5′-cyclic adenosine monophosphate) synephrine HCL R-beta-methylphenylethylamine N-Methyl-B-phenylethylamine yohimbe Methyl-hordenineIncreased REE 59 ± 26 kcal·6 hrs, serum epinephrine, norepinephrine, glycerol, systolic and diastolic BPBloomer et al. 2009 [37]

Healthy men and women ( )Caffeine anhydrous toothed clubmoss (Huperzia serrata) yerba mate (Llex Paraguariensis) 3′-5′-CAMP (3′-5′-cyclic adenosine monophosphate) synephrine HCL R-beta-methylphenylethylamine N-mehtyl-B-phenylethylamine yohimbe Methyl-hordenineIncreased REE, increased HR, no change in BPHoffman et al. 2009 [38]

Healthy men and women ( )Caffeine anhydrous toothed clubmoss (Huperzia serrata) yerba mate (Llex paraguariensis) 3′-5′-CAMP (3′-5′-cyclic adenosine monophosphate) synephrine HCL R-beta-methylphenylethylamine N-mehtyl-B-phenylethylamine yohimbe Methyl-hordenineIncreased REE 45, 60, 120 minutes after ingestion with no change in HR or BPJitomir et al. 2008 [39]

Healthy men and women ( )Caffeine anhydrous, guarana, yerba mate green tea extract, L-carnitine L-tartrate, pathothenic acid, chromium picolinate, proprietary blends containins, AssuriTea green tea extract, Salvia sclarea, raspberry ketones and Capsicum annum extract, plus l-tyrosine, Salix alba, Zingiber officinale, fucus vesiculosus, Panax ginseng, bioperineWIncreased REE 60, 120, 180, 240 minutes after ingestionOutlaw et al. 2013 [40]

Healthy men and women ( )Supplement caffeine 200 mg, capsicum extract 33.34 mg, Niacin 20 mg, Bioperine 5 mgIncreased REE 50 minutes after consumption with elevated HR and BPRyan et al. 2009 [32]

40 male and 40 female healthy young subjects1 mg capsinoids in 199 mg of rapeseed oil and medium-chain triglyceridesNo change in REE or weight but increased fat oxidationSnitker et al. 2009 [41]

10 healthy subjects per treatment 600 mg naringin, 50 mg p-synephrine
100 mg hesperidin, 50 mg p-synephrine, 600 mg naringin
1000 mg hesperidin, 50 mg p-synephrine, 600 mg naringin
Increased REE 129 kcal
Increased REE 183 kcal
Increased REE 79 kcal
Stohs et al. 2011 [17]

8 male and 10 female healthy young subjects442 mg of a proprietary: 100 mg of caffeine, 230 mg of green tea extract, L-tyrosine, L-taurine, chocamine, white willow extract, yohimbine-HCl, vinpocetine Increased REE 60, 120, 180 minutes after ingestionWilborn et al. 2009 [42]

Healthy men and women ( )Caffeine, citrus aurantium, garcinia, cambogia and chromium polynicotinateSignificantly increased REE at 60, 120, 180 minDalbo et al. 2008 [43]

18 healthy young men 1.5 mg capsinoids in 199 mg of rapeseed oil and medium-chain triglyceridesEE increased by 15.2 kJ/h (BAT+) (5 kcals/hour) groups 1 hours after ingestionYoneshiro et al. 2012 [44]

Effects of extended consumption of dietary supplements on energy expenditure

Healthy men and women ( )pantothenic acid, 40 mg; green tea leaf extract 200 mg; guarana extract (198 mg of caffeine), 550 mg; bitter orange (9 mg of synephrine), 150 mg; white willow bark extract (7.5 mg of salicin), 50 mg; ginger root, 10 mg; proprietary blend (L-tyrosine, L-carnitine, naringin), 375 mg, phenylephrine (20 mg)Increased REE with increased body weightGreenway et al. 2006 [36]

Obese subjects ( )Green tea extract 750 mg L-tyrosine 609 mg caffeine 151 mg Cayenne 225 mg calcium 1965 mg Supplement increased REE by 87.3 kJ (21 kcal) sustained for 8 weeks with reduced body fat massBelza et al. 2007 [35]