Sublingual Delivery of Frovatriptan: An Indication of Potential Alternative Route

Table 6

Steady state flux () and permeability coefficient () values of frovatriptan through sublingual mucosae at the end of 2 hours [V = mucosa of ventral surface of tongue; F = mucosa of floor of moth; ratio = of V/ of F].

Batch code (→)		C2	F2	F6	F9
(mg cm^−2min^−1)	V	0.22	0.18	0.22	0.32
	F	0.13	0.11	0.10	0.21
(cm min^−1)	V	0.18	0.14	0.18	0.26
	F	0.10	0.09	0.08	0.17
Ratio (→)		1.80	1.56	2.25	1.53