Evaluation of Antioxidant, Immunomodulatory Activities, and Safety of Ethanol Extract and Fractions of Gongronema latifolium Fruit

Table 2

Effect of extract and fractions of G. latifolium fruit on serum catalase and superoxide dismutase activity.

Treatment	Dose (mg/kg)	Catalase (U/L)		Superoxide dismutase (U/L)
		Pretreatment	Posttreatment	Pretreatment	Posttreatment
Ethanol extract	200	1.8 ± 0.4	2.5 ± 0.6	11.9 ± 0.5	^*22.0 ± 0.8
	400	2.0 ± 0.5	^*2.8 ± 0.8	11.8 ± 0.4	^*22.3 ± 0.6
Ethyl acetate fraction	200	2.1 ± 0.6	^*2.9 ± 0.4	11.7 ± 0.5	^*22.4 ± 0.9
	400	1.9 ± 0.5	^*3.1 ± 0.7	11.7 ± 0.3	^*24.8 ± 0.7
Methanol fraction	200	2.0 ± 0.4	^*3.1 ± 0.6	11.8 ± 0.5	^*23.3 ± 0.8
	400	2.1 ± 0.5	^*3.3 ± 0.7	11.9 ± 0.4	^*25.5 ± 0.9
Vitamin C	200	2.0 ± 0.4	^*2.9 ± 0.6	11.8 ± 0.5	^*23.4 ± 0.8
10% tween 80	10 mL/kg	2.0 ± 0.4	1.5 ± 0.8	11.7 ± 0.5	9.3 ± 0.6

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