Evaluation of Antioxidant, Immunomodulatory Activities, and Safety of Ethanol Extract and Fractions of Gongronema latifolium Fruit

Table 3

Effect of the extract and fractions on carbon clearance and delayed type hypersensitivity reaction (DTHR).

Treatment	Dose (mg/kg)	Phagocytic index	DTHR response
Ethanol extract	200	0.012 ± 0.003	^*0.10 ± 0.008
	400	^*0.020 ± 0.002	^*0.11 ± 0.005
Ethyl acetate fraction	200	^*0.021 ± 0.001	^*0.10 ± 0.006
	400	^*0.043 ± 0.004	^*0.11 ± 0.004
Methanol fraction	200	^*0.025 ± 0.003	^*0.11 ± 0.004
	400	^*0.052 ± 0.003	^*0.13 ± 0.006
Noni capsule	50	^*0.061 ± 0.005	^*0.17 ± 0.008
Normal saline	10 mL/kg	0.010 ± 0.002	0.05 ± 0.001

= 5, P < 0.05.