Research Article
Evaluation of Antioxidant, Immunomodulatory Activities, and Safety of Ethanol Extract and Fractions of Gongronema latifolium Fruit
Table 4
Effect of the extract and fractions on total and differential leukocyte counts.
| | Treatment | Dose (mg/kg) | TLC (mm3) | DLC (%) | | Neutrophil | Lymphocyte |
| | Ethanol extract | 200 | 4600 ± 21 | 34.75 ± 1.2 | 65.25 ± 3.3 | | 400 | *4725 ± 26 | 23.00 ± 1.4 | 75.50 ± 5.0 | | Ethyl acetate fraction | 200 | *4900 ± 23 | 29.75 ± 1.0 | 70.13 ± 3.1 | | 400 | *5850 ± 28 | *40.75 ± 1.6 | 59.25 ± 2.8 | | Methanol fraction | 200 | *4900 ± 20 | 23.25 ± 1.4 | 75.25 ± 2.2 | | 400 | *5325 ± 22 | 19.50 ± 1.1 | 79.50 ± 2.6 | | Noni capsule | 50 | *7150 ± 24 | 20.25 ± 1.2 | 79.65 ± 1.4 | | Normal saline | 10 mL/kg | 4550 ± 19 | 32.00 ± 1.3 | 67.75 ± 1.7 |
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= 5, P < 0.05.
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