Evaluation of Antioxidant, Immunomodulatory Activities, and Safety of Ethanol Extract and Fractions of Gongronema latifolium Fruit

Table 5

Haemagglutination antibody titer: primary antibody response.

Treatment	Dose (mg/kg)	Ovalbumin antigen		Tetanus toxoid antigen
		Ethanol extract	200	^*0.33 ± 0.006	^*0.13 ± 0.004	^*0.14 ± 0.006	^*0.08 ± 0.003
400	^*0.30 ± 0.004		^*0.18 ± 0.010	^*0.15 ± 0.008	^*0.14 ± 0.006
Ethyl acetate fraction	200	^*0.17 ± 0.003	^*0.10 ± 0.002	^*0.12 ± 0.005	^*0.10 ± 0.003
	400	^*0.19 ± 0.006	^*0.12 ± 0.004	^*0.15 ± 0.007	^*0.11 ± 0.005
Methanol fraction	200	^*0.19 ± 0.011	^*0.10 ± 0.003	^*0.14 ± 0.005	^*0.12 ± 0.004
	400	^*0.21 ± 0.020	^*0.14 ± 0.015	^*0.17 ± 0.009	^*0.16 ± 0.007
Noni capsule	50	^*0.62 ± 0.026	^*0.52 ± 0.039	^*0.56 ± 0.021	^*0.43 ± 0.026
Normal saline	10 mL/kg	0.05 ± 0.002	0.04 ± 0.007	0.04 ± 0.002	0.03 ± 0.002

= 5, P < 0.01.