Scientific Validation of Gentiana kurroo Royle for Anti-Inflammatory and Immunomodulatory Potential

Table 1

Effect of different extracts of Gentiana kurroo Royle at a dose of 250 mg/kg on Carrageenan-induced paw edema in rats (mean ± S.E) (𝑛=4).

Serial number	Groups	Dose (mg/kg)	Initial paw volume (mL)	Paw volume after 4 h (mL)	Edema (4 h)	% age inhibition (4 h)
1	Control	NS	2.07±0.075	1.02±0.048	1.05±0.029^a	—
2	GMT	250	1.55±0.029	1±0.041	0.55±0.029^b	47.62
3	GET	250	1.8±0.071	1±0.041	0.8±0.071^ac	23.81
4	GPT	250	1.95±0.056	0.97±0.041	0.97±0.074^bc	7.62
5	GAQ	250	1.72±0.025	0.97±0.025	0.75±0.029^b	28.57
6	Diclo	20	1.57±0.025	1.1±0.041	0.47±0.025^c	55.24

Values along the same column with different superscripts are statistically significant to each other using Tukey’s HSD test (𝑃<0.05). GMT: methanolic extract; GET: ethyl acetate extract; GPT: petroleum ether extract; GAQ: aqueous extract; Diclo: diclofenac.