Hyaluronan Is Not a Ligand but a Regulator of Toll-Like Receptor Signaling in Mesangial Cells: Role of Extracellular Matrix in Innate Immunity
Figure 5
Effect of hyaluronidase on the specific stimulation of TLR2 and TLR4. Both cell types were incubated with different concentrations of specific TLR ligands ((a) TLR2 and (b) TLR4) with and without hyaluronidase to demonstrate the effect of hyaluronidase on TLR-stimulation. PAM: PAM3CysSK4; HYAL: hyaluronidase; data are means ± SD, ns: not significant, .
