Stability Indicating RP-HPLC Method for the Simultaneous Determination of Atorvastatin Calcium, Metformin Hydrochloride, and Glimepiride in Bulk and Combined Tablet Dosage Form

Table 1

System suitability parameters of ATR, MET, and GLM.

Parameter	MET		ATR		GLM		Specifications [22]
	Mean ± SD	%RSD	Mean ± SD	%RSD	Mean ± SD	%RSD
Rt	2.57 ± 0.04	1.75	7.06 ± 0.13	1.90	9.39 ± 0.11	1.23	RSD ≤ 2
TF	1.25 ± 0.01	0.92	1.15 ± 0.01	1.00	1.11 ± 0.01	0.89	TF ≤ 2
Rs	9.38 ± 0.18	1.92	—	—	5.27 ± 0.06	1.18
TP	3556 ± 64	1.82	4872 ± 93	1.92	6280 ± 30	0.489	> 2000

Rt; retention time, TF: tailing factor, Rs: resolution, and TP: theoretical plates; .