Stability Indicating RP-HPLC Method for the Simultaneous Determination of Atorvastatin Calcium, Metformin Hydrochloride, and Glimepiride in Bulk and Combined Tablet Dosage Form

Table 2

Intra and Interday accuracy and precision of ATR, MET, and GLM.

Conc. in g/mL	MET		ATR		GLM
	Mean ± SD	%RSD	Mean ± SD	%RSD	Mean ± SD	%RSD
Intraday ()
10	—	—	99.82 ± 1.151	1.153	105.02 ± 0.236	0.225
20	99.36 ± 0.137	0.137	106.73 ± 1.567	1.468	104.27 ± 0.835	0.801
50	100.08 ± 1.994	1.992	98.95 ± 0.222	0.225	100.78 ± 0.303	0.301
100	102.67 ± 0.393	0.383	102.04 ± 0.204	0.200	103.14 ± 0.610	0.591
Interday ()
10	—	—	99.15 ± 0.593	0.598	103.57 ± 1.422	1.373
20	100.43 ± 1.672	1.665	103.17 ± 1.328	1.287	102.45 ± 0.355	0.346
50	98.20 ± 1.007	1.025	100.22 ± 0.695	0.694	100.82 ± 0.217	0.215
100	101.45 ± 0.207	0.204	98.37 ± 1.338	1.360	100.92 ± 1.082	1.072