Current State of Topical Antimicrobial Therapy in Management of Early Childhood Caries

Table 1

Brief overview of various topical antimicrobial agents.

Author Name	Agent used	Comments
Marinho et al. 2013 [14]	Fluoride varnish	Substantial caries inhibiting effect of fluoride varnish in both permanent and primary dentition
Rosenblatt et al. 2009 [23]	Silver diamine fluoride	SDF can be an effective agent in preventing new caries lesion and in arresting dental caries in primary teeth.
Petti and Hausen 2006 [31]	Chlorhexidine varnish	CHX gel showed moderate anti-MS effect but negligible caries preventive effect.
Simratvir et al. 2010 [32]	Povidone iodine	Povidone iodine application can be a good alternative to control caries in children affected with ECC.
Zhan et al. 2012 [38]	Xylitol wipes	7 times fewer children from the xylitol-wipe group developing new caries compared with the placebo group
He et al. 2006 [40]	Liquorice	Glycyrrhizol A and B in liquorice have demonstrated substantial antimicrobial activity against S. mutans