Predictors of Mortality among United States Veterans with Human Immunodeficiency Virus and Hepatitis C Virus Coinfection

Table 2

Association of HCV status with mortality among HIV infected veterans in a multivariable regression model.

Variables	Model 1; 𝑁=8030	Model 2; 𝑁=4521	Full model; 𝑁=4521
HCV	1.78 (1.59, 1.96)	1.66 (1.44, 1.93)	1.58 (1.36, 1.84)
Age (per 10 yrs)	1.60 (1.51, 1.70)	1.51 (1.40, 1.64)	1.32 (1.21, 1.44)
Male	1.00 (0.70, 1.43)	1.07 (0.60, 1.89)	0.98 (0.55, 1.73)
DLD	—	3.73 (3.29, 4.24)	2.17 (1.88, 2.5)
Black versus white	—	—	0.86 (0.74, 1)
Hispanic versus white	—	—	0.79 (0.61, 1.03)
BMI (kg/m^2)	—	—	0.94 (0.92, 0.95)
Smoking	—	—	0.97 (0.82, 1.14)
Hypertension	—	—	0.98 (0.85, 1.14)
Diabetes	—	—	1.45 (1.22, 1.71)
COPD	—	—	1.44 (1.19, 1.75)
Anemia	—	—	1.59 (1.36, 1.86)
CKD	—	—	1.74 (1.5, 2.02)
CAD	—	—	1.78 (1.42, 2.23)
Stroke	—	—	1.28 (0.87, 1.89)
PVD	—	—	0.82 (0.54, 1.23)
Thromboembolism	—	—	0.44 (0.11, 1.79)
Cancer	—	—	1.5 (1.26, 1.79)
Drug abuse	—	—	1.06 (0.9, 1.26)
Alcohol abuse	—	—	1.14 (0.96, 1.35)
Major depression	—	—	1.01 (0.82, 1.24)
CD4 count (per 100 clls/uL)	—	—	0.9 (0.88, 0.93)

Model 1: 8030 individuals with HIV infection had available data on HCV status, age, and sex.
Model 2: 4521 individuals with HIV infection had available data on HCV status, age, sex, and decompensated liver disease.
Model 3: 4521 individual with HIV infection had available data on all the 22 variables included in model.
ALT: alanine transaminase; AST: aspartate transaminase; BMI: body mass index; CAD: coronary artery disease; CKD: chronic kidney disease; COPD: chronic obstructive pulmonary disease; DLD: decompensated liver disease; PVD: peripheral vascular disease.