Relationship between Metabolic Fluxes and Sequence-Derived Properties of Enzymes

Figure 2

The multiple linear regressions showing changes of the metabolic fluxes as dependent variables upon the two average AA properties of the yeast Saccharomyces cerevisiae enzyme sequences, as specified in the Table 1. The data ((a), (c)) represent models I and II, respectively (Table 2). The observed versus predicted plots ((b), (d)) for the values of dependent variables ((a) and (c), resp.). The predicted values were calculated from the regression equations: flux (model I) = Flux: (%, ); flux (model II) (%, ). All the multiple and pair correlations ((a), (b), (c), (d)) are significant at the nonparametric assessment (Kendall’s , Spearman’s correlation coefficients).

(a)

(b)

(c)

(d)