Relationship between Metabolic Fluxes and Sequence-Derived Properties of Enzymes

Figure 3

The changes in the percentage of explained variance (□) and the values of corrected Akaike’s information criterion (AIC c) (▲) on the growing number of independent variables (the average AA properties of enzyme sequences) included in the multiple regression. Variables in the model (Tables 1 and 2, model II): 1—, 2—, , 3—, , , 4—, , , , 5—, , , , , 6—, , , , , , 7—, , , , , , , 8—, , , , , , , , 9—, , , , , , , , , 10—, , , , , , , , , . (a) The scale WV10 correlates with the NMR parameters and pK values of AA [18]. (b) The scale WV9 correlates with the indices of protein backbone topography and relative mutability of AA [18].