Review Article

Surgical Management of Malignant Pleural Mesothelioma: Impact of Surgery on Survival and Quality of Life—Relation to Chemotherapy, Radiotherapy, and Alternative Therapies

Table 3

Study characteristics. EPP.

Author/yearCentrePeriodDesign ChemotherapyEPPRxF/U

Schipper et al., 2008 [20]Mayo clinic1985–2003Retrospective review of
prospective database
Unknown77Unknown5 years
Luckraz et al. 2010 [21]University Hospital of Wales, UK1980–2010Retrospective review of
prospective database
All referred49 of which 15 TMTAll referred5 years
Flores et al., 2008 [22]3 cancer centres in USA1990–2006Retrospective review Clinical trial dependent385 totalClinical trial dependent5 years
Okada et al., 2008 [23]Japan single centre1986–2006Retrospective review 53155 years
Aziz et al., 2002 [15]Scotland single centre1989–1998Retrospective review5164515 years
Lang-Lazdunski et al., 2011 [28]Guy’s and St Thomas, UK2004–2011Prospective observational2222175 years
Krug et al., 2009 [30]Multicentre, US2003–2006Randomised trial77 neoadjuvant54445 years
Buduhan et al., 2009 [31]Washington, USA1997–2008Retrospective46 neoadjuvant46446 years
De Perrot et al., 2009 [32]Single centre, Canada2001–2007Retrospective60 neoadjuvant45305 years
Weder et al., 2007 [33]Multicentre, Europe 2000–2003Prospective58 neoadjuvant45365 years
Rea et al., 2013 [34]4 centres, Italy2005–2010Retrospective52 neoadjuvant41322 years
Sugarbaker et al., 1999 [29]3 centres, USA1980–1997Retrospective183 adjuvant1831835 years
Van Schil et al., 2010 [35]11 centres, Europe2005–2007Prospective trial58 neoadjuvant42373 years
Treasure et al., 2011 [16]12 centres UK2005–2008RCT241982 years
Rena and Casadio 2012 [25]Single centre, Italy1998–2009Retrospective4040403 years
Tonoli et al., 2011 [36]3 centres, Italy2005–2010Retrospective4856566 years