Effect of Aerobic Exercise Training on MDA and TNF-α Levels in Patients with Type 2 Diabetes Mellitus
Table 2
Comparisons of clinical and laboratory characteristics baseline and after 12-week period in aerobic exercise and control group (mean ± SD).
Variable
Baseline aerobic exercise group ()
After 12-week period in aerobic exercise group ()
Baseline control group ()
After 12-week period in control group ()
value
value
HbA1c (%)
6.8 ± 0.9
6.6 ± 1.0
6.8 ± 0.8
6.9 ± 1.1
0.1
0.4
BMI (kg/m2)
30.9 ± 4.6
30.4 ± 4.3
30.6 ± 4.8
30.5 ± 4.6
0.017
0.4
Waist circumference (cm)
101.9 ± 8.6
100.0 ± 8.2
99.7 ± 10.7
99.7 ± 10.5
0.012
0.7
Systolic arterial pressure (mmHg)
129.0 ± 12.9
122.5 ± 11.7
124.1 ± 14
124.3 ± 15.0
0.027
0.9
Diastolic arterial pressure (mmHg)
79.5 ± 7.1
75.8 ± 7.7
78.0 ± 10.5
77.0 ± 8.1
0.042
0.5
LDL-c (mg/dL)
106.4 ± 34.5
104.1 ± 32.1
116.0 ± 35.5
120.0 ± 31.5
0.7
0.6
HDL-c (mg/dL)
39.8 ± 9.1
40.9 ± 12.2
41.3 ± 8.6
43.0 ± 9.5
0.2
0.07
TG (mg/dL)
159.4 ± 90.2
144.0 ± 66.3
149.9 ± 80.3
164.0 ± 85.6
0.2
0.1
TC (mg/dL)
176.2 ± 42.0
172.0 ± 38.4
190 ± 45.4
193.0 ± 44.5
0.5
0.6
TNF-α (pg/mL)
14.2 ± 5.9
13.9 ± 5.2
14.1 ± 5.1
14.8 ± 5.7
0.7
0.2
MDA (nmol/mL)
6.56 ± 0.9
6.06 ± 1.0
6.61 ± 1.0
6.45 ± 0.8
0.046
0.2
BMI: body mass index, LDL-c: low density lipoprotein cholesterol, HDL-c: high density lipoprotein cholesterol, TG: triglyceride, TNF- α: tumor necrosis factor-alpha, MDA: malondialdehyde, before versus after 12-week period in aerobic exercise group, before versus after 12-week period in control group.
