Table 1: Synthetic ligands at melatonin receptors.

NumberCompound*Type of ligandReference

Melatonin derivatives
1843478.tab.001aAgonist
MT1 and MT2
[65]
2843478.tab.001bAgonist MT1,
antagonist MT2
[66]
3843478.tab.001cAgonist MT3[67]

Tri- and tetracyclic compounds
4843478.tab.001dAntagonist MT2[68]
5843478.tab.001eAgonist MT2[68]
6843478.tab.001fAgonist
MT1 and MT2
[65]
7843478.tab.001gAgonist
MT1 and MT2
[30]

Naphthalene and tetralin analogues
8843478.tab.001hAgonist
MT1 and MT2
[69]
9843478.tab.001iAntagonist MT2[70]

“Dimeric ligands”
10843478.tab.001jAgonist MT1[70]
11843478.tab.001kAntagonist MT1[71]

Thiazolidine analogues
12843478.tab.001lAgonist RZR/ROR[72]

For ligands with low selectivity to the MT1 and MT2 and also for the MT3 and RZR/ROR ligands, the values of the dissociation constants for receptor complex are shown as , , , , respectively. For ligands of high selectivity, the ratios of the dissociation constants are given, or .