Research Article

Prevalence and Genetic Characterization of Carbapenem- and Polymyxin-Resistant Acinetobacter baumannii Isolated from a Tertiary Hospital in Terengganu, Malaysia

Table 2

Mutational points found in the polymyxin-resistant determinants among the 14 polymyxin-resistant A. baumannii isolates as compared to susceptible isolates.

IsolateMutations
pmrA lpxD lpxC lpsB

AC12P102HS102T, V141I, and R173GK141RH181Y
AC30P102HS102T, V141I, and R173GK141RH181Y
AC3P102H T104K, I178VS158R
AC13P102HT121A, N151D, and G169SS158R
AC16P102HE50D, V141I K141RH181Y
AC17P102HE50D, V141IK141RH181Y
AC18P102HE50D, V141IK141RH181Y
AC20P102HT15A, T121A, N151D, and G186SK141R, S158RH181Y
AC21P102HT15A, T121A, N151D, and G186SK141R, S158R
AC22P102HE50D, S102T, and I178VK141R, S158RH181Y
AC27P102H S102T, G169S, and R173GS158RH181Y
AC38P102HS102T, G169S, I178V, and G186S, K141R
AC51P102HE50D, R173GK141R, S158R
AC61P102HI178V, S181N K141R, S158R

Note: no mutation was detected in pmrC, pmrB, and lpxA.