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Journal of Allergy
Volume 2010 (2010), Article ID 491928, 11 pages
http://dx.doi.org/10.1155/2010/491928
Review Article

Neural Pathways in Allergic Inflammation

1Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, Brazil
2Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, Brazil

Received 2 October 2010; Revised 30 November 2010; Accepted 8 December 2010

Academic Editor: Redwan Moqbel

Copyright © 2010 L. Mirotti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Allergy is on the rise worldwide. Asthma, food allergy, dermatitis, and systemic anaphylaxis are amongst the most common allergic diseases. The association between allergy and altered behavior patterns has long been recognized. The molecular and cellular pathways in the bidirectional interactions of nervous and immune systems are now starting to be elucidated. In this paper, we outline the consequences of allergic diseases, especially food allergy and asthma, on behavior and neural activity and on the neural modulation of allergic responses.