Allergic Potential and Immunotoxicity Induced by Topical Application of 1-Chloro-4-(Trifluoromethyl)Benzene (PCBTF) in a Murine Model

Table 1

Phenotypic analysis after in vivo PCBTF treatment.

Dose group	IgE+B220+ (% lymphocyte population)		B220+ (% lymphocyte population)
	%	Cells × 10^6	%	Cells × 10^6
DLN
Acetone	1.1 ± 0.3	0.09 ± 0.02	11.5 ± 1.9	1.1 ± 0.16
PCBTF
50%	4.5 ± 2.1	0.13 ± 0.02	14.0 ± 3.1	2.0 ± 0.53
75%	3.5 ± 0.4	0.12 ± 0.02	12.6 ± 0.9	1.8 ± 0.24
100%	2.4 ± 0.6	0.14 ± 0.01	12.0 ± 1.4	1.8 ± 0.23
Spleen
Acetone	4.2 ± 2.4	2.1 ± 1.01	43.4 ± 4.7	2.3 ± 1.06
PCBTF
50%	4.7 ± 2.5	2.2 ± 1.33	38.9 ± 1.8	1.7 ± 1.12
75%	1.4 ± 0.1	1.7 ± 1.58	42.6 ± 1.7	1.9 ± 0.96
100%	2.2 ± 0.9	2.1 ± 0.98	40.1 ± 1.4	2.1 ± 1.21