Arginase and Arginine Dysregulation in Asthma

Table 1

Pharmacologic enzyme inhibitors.

Inhibitor	Specificity	Route	Reference
L-NAME	Nonselective NOS	Oral	[20, 42, 43]
NOHA	Arginase	Inhaled	[39, 44, 45]
nor-NOHA	Arginase	Inhaled, intraperitoneal	[19, 38, 42, 46, 47]
L-NMMA	Arginase	Inhaled	[48]
ABH	Arginase	Inhaled	[49]
BEC	Arginase	Oropharyngeal aspiration	[50]

List of abbreviations: N (G-) nitro-L-arginine methyl ester (L-NAME), nitric oxide synthase (NOS), N-hydroxy-L-arginine (NOHA), N-hydroxy-nor-L-arginine (nor-NOHA), N^G-monomethyl-L-arginine (L-NMMA), 2(S)-amino-6-boronohexanoic acid (ABH), S-(2-boronoethyl)-l-cysteine (BEC).