Table 1: Pharmacologic enzyme inhibitors.

InhibitorSpecificityRouteReference

L-NAMENonselective NOSOral[20, 42, 43]
NOHAArginaseInhaled[39, 44, 45]
nor-NOHAArginaseInhaled, intraperitoneal[19, 38, 42, 46, 47]
L-NMMAArginaseInhaled[48]
ABHArginaseInhaled[49]
BECArginaseOropharyngeal aspiration[50]

List of abbreviations: N (G-) nitro-L-arginine methyl ester (L-NAME), nitric oxide synthase (NOS), N-hydroxy-L-arginine (NOHA), N-hydroxy-nor-L-arginine (nor-NOHA), NG-monomethyl-L-arginine (L-NMMA), 2(S)-amino-6-boronohexanoic acid (ABH), S-(2-boronoethyl)-l-cysteine (BEC).