Review Article
The Pivotal Role of Airway Smooth Muscle in Asthma Pathophysiology
Table 6
Promigratory factors for human ASM cells.
| Factors | References |
| Growth factors/cytokines/chemokines | | FGF2, PDGF, TGF-α (TNFSF2), TGF-β | [229, 230] | IL-1β, IL-17A, IL-17F, IL-22 | [123, 230] | CCL5, 11, 19 | [128, 231, 232] | CXCL8 | [231] | Leukotriene E4 | [233] | ECM components | | Collagens I, III, V | [233] | Fibronectin, laminin | [233] | Enzymes | | Matrix metalloproteinase- (MMP-)3 | [234] | Others | | Thrombin | [235] | Urokinase plaminogen activator | [236] |
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