Comparison between Airway Responses to High versus Low Molecular Weight Compounds in Occupational Asthma

Table 1

Characteristics of the compounds used for performing specific inhalation tests (SIC), concentrations used during SIC and duration of the exposure.

Agent	Control	Number of subjects	Challenge concentration	Time exposure
TDI vapours	Diluent	37	0.002–0.003 ppm	30–120′
Flour dust	Lactose dust	20	0.3–0.5 mg/m^3	30′
Wood dusts	Lactose dust	3	0.3–0.5 mg/m^3	30′
Persulfate salts	Lactose dust	6	0.05–0.1 mg/m^3	30′
Aziridine	Lactose dust	2	0.03–0.05 mg/m^3	30′
Latex solution	Normal saline	3	<0.0001 mg/m^3	30′
Tobacco dusts	Lactose dust	1	0.3–0.5 mg/m^3	30′
Phenolic resins and Detergents vapours	Diluent	2	Not measured*	30′

*Subjects simulated the job activity in laboratory.