Review Article
[Retracted] Immunopathology and Immunogenetics of Allergic Bronchopulmonary Aspergillosis
Table 1
Genetic risk factors in the development of allergic bronchopulmonary aspergillosis.
| (i) HLA-DR restriction and HLA-DQ protection | (a) HLA-DR2 restriction | HLA-DRB1*1501 and *HLA-DRB1*1503 | (b) HLA-DR5 | HLA-DRB1*1104 | (c) HLA-DQ2 protective, decreased in ABPA | DQB1*0201 | (ii) IL-4RA polymorphisms | (a) IL-4RA ile75val | (iii) IL-10 polymorphisms | (a) Promoter −1082 GG genotype | (iv) Surfactant protein A2 (SP-A2) polymorphisms | (a) SP-A2 ala91pro | (v) Cystic fibrosis transmembrane conductance regulator (CFTR) mutations | (a) Heterozygous CFTR mutations in asthmatic patients with ABPA | (vi) Toll-like receptor (TLR) polymorphisms | (a) TLR9 T-1237C polymorphism |
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