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Journal of Allergy
Volume 2012 (2012), Article ID 179658, 4 pages
http://dx.doi.org/10.1155/2012/179658
Review Article

Eosinophilic Esophagitis in Pediatrics: The Worst of all Possible Allergy Worlds?

Department of Pediatrics, Creighton University School of Medicine, Omaha, NE 68131, USA

Received 10 April 2011; Revised 2 June 2011; Accepted 11 July 2011

Academic Editor: John Bastian

Copyright © 2012 Russell J. Hopp. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Eosinophilic esophagitis (EoE) is a relatively uncommon allergic disease. Presenting with variable gastrointestinal symptoms, the definitive diagnosis is made after esophageal visualization and histological confirmation of excessive esophageal eosinophils. The scientific discovery of the pathophysiology of EoE has been aided by its relationship to other common and well-recognized allergic diseases. Similarities and important differences have emerged to distinguish EoE as a significant pediatric allergic disease with unique medical care requirements.