Table 3: Side effects of patients treated with maintenance dose.

Group A Group B Group C Total Patients 1 7 6 14 maintenance dose of Apis m. 1 6 5 12 maintenance dose of Vespula spp. 1 1 2 Local large reaction* (%) — 2(33.3) 4(66.6) 6 Systemic anaphylactic reaction§ (%) 1(12.5) 5(62.5) 2(25.0) 8 Grade I 1 4 1 6 Grade II — 1 1 2

*A large local reaction is defined as a swelling at the site of more than 10 cm lasting for more than 24 hours [31]. §A systemic anaphylactic reaction (SAR) was classified with modified classification of Müller [9].