Review Article

Altered CD38/Cyclic ADP-Ribose Signaling Contributes to the Asthmatic Phenotype

Table 1

A partial list of miR-140-3p gene targets predicted by TargetScan and microRNA.org.

Receptors and channelsARHGAP3, IRGQ, SCN3A, NKIRAS2, GPR12, GIT1, GABRB2, PLEKHA1, KCNA7, TRPM7, SGSM1, GPR158, REEP5, SGIP1, GAB2, RASGEF1B, FKBP1A, and RGS1
Cytokine/chemokine regulationSOCS4, CDK6, MMP16, TGIF2, ADAM17, ITK, CHL1, ADAM9, CXCL11, IL8, IL6, and CXCL6
Related to transcriptional regulationCREB1, SP3, TAF2, SP4, TCEB3, SIRT1, E2F7, KLF4, RAB2A, FOX2, NFYA, NKRF, HDAC4, GABPB1, SP3, KLF5, IKB, and KB
MAPK and PKC/MTOR pathwaysPTEN, RAP1B, RPS6KA3, RICTOR, MAPK1, PPFIBP1, CDS2, MARCKS, MAP2K6, and IL24,
Related to actin and myosinMYLK4, MAPRE3
Related to proliferationZNF3