Cyclin D1 in ASM Cells from Asthmatics Is Insensitive to Corticosteroid Inhibition

Table 1

Subject demographics.

Subject no.	Gender	Disease	FEV1 (% Pred)	FVC (% Pred)	FEV1 : FVC (%)	Smoker	Height	Weight	Experiments
1	F	Ca							1, 2
2	F	A	64%	70%	76%	Ex-smoker			1, 3
3	F	Ca							1, 2
4	M	A	82%			No			1, 3
5	F	NSCCa				Yes			1, 2
6	F	A	2.04 L	2.5 L		No	158 cm	64 kg	1, 3
7	M	NSSCa	2.12 L	3.35 L		Ex-smoker	173 cm	76 kg	1, 2
8	F	A	1.87 L	2.32 L		No	168 cm	57 kg	1, 3
9	F	Bronchiolitis obliterans							1, 2
10	M	A	3.75 L	5.9 L		No	179 cm	110 kg	1, 3
11	M	Emphysema							1, 2
12	M	A				No			1, 3
13	F	Emphysema				Yes			1, 2
14	M	A	4.77 L	5.32 L		Yes			1, 3
15	F	Emphysema	27% (0.51 L)	67% (1.5 L)			153 cm		1, 2
16	M	Emphysema, α-1 antitrypsin deficiency	15% (0.61 L)	66% (3.42 L)					4
17	M	A	57%	61%	77%	No			4
18	M	COPD	20%	65%	24%	Yes			4
19	M	Ca + A				Ex-smoker			4
20	M	Ca	1.95 L	2.5 L		Ex-smoker	169 cm	79 kg	4
21	M	A							4

Abbreviations used: Ca, carcinoma; A, asthma; NSCCa, nonsmall cell carcinoma; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 second (% predicted); FVC, forced vital capacity (% predicted).