L-Carnitine Improves the Asthma Control in Children with Moderate Persistent Asthma

Table 5

Emergency room visit, total hospital admissions, blood eosinophils, and serum IgE in patient subgroups before and after carnitine supplementation and the placebo group.

		Subgroup A (with L-Carnitine); (𝑛=25)	Subgroup B (Placebo); (𝑛=25)	t	𝑃
Emergency room visit	bef.	3.1±1.01	3.4±1.0	1.2	>0.05
	aft	1.5±0.6	2.6±0.9	4.68	<0.001*
Total Hospital admissions	bef.	1.5±0.6	1.8±0.7	1.9	>0.05
	aft	0.44±0.5	1.8±0.6	7.5	<0.001*
Oral steroid	bef.	2.16±0.74	2.12±0.72	0.21	>0.05
	aft	1.2±0.5	1.6±0.5	2.8	<0.01*
Serum IgE (kU/L)	bef.	328±89	322±114	0.21	>0.05
	aft	253±62	290±106	1.6	>0.05
Blood eosinophils (%)	bef.	5.8±2.1	6.04±2.1	0.38	>0.05
	aft	3.1±0.8	4.4±1.2	4.2	<0.001*

(*) 𝑃<0.05 is significant There were significant decreases in the frequency of emergency room visit, total hospital admissions, and the intake of oral steroids between L-Carnitine-supplemented children compared to placebo group during the study period. The blood eosinophils % decreased significantly after treatment with L-Carnitine in asthmatic group. It was significantly lower in L-Carnitine treatment group than in placebo group. Serum Ig E showed no significant difference in treatment and placebo group (both before and after treatment).