Late Type of Bronchial Response to Milk Ingestion Challenge: A Comparison of Open and Double-Blind Challenge
Table 1
Characteristics of the patients and control subjects.
Patients
Control subjects
Total
LAR
NAR
Age (years)
31 ± 6
30 ± 7
32 ± 5
27 ± 6
Gender (M/F)
25/29
11/15
14/14
5/7
Disease history (years)
4.7 ± 1.3
3.5 ± 1.6
5.1 ± 1.0
4.2 ± 1.5
Asthmatic attacks per month
4 ± 1
5 ± 2
2 ± 1
3 ± 2
FEV1 (% predicted)
94.8 ± 4.2
93.1 ± 5.5
97.0 ± 3.3
95.6 ± 4.3
FVC (% predicted)
99.2 ± 1.1
96.4 ± 3.0
100.1 ± 1.4
98.0 ± 4.3
Blood leukocyte count (×109 /L)●
7.1 ± 0.8
7.5.0 ± 1.2
8.0 ± 0.4
7.9 ± 1.5
Blood eosinophil count (×106 /L)●●
355 ± 60
387 ± 56
329 ± 70
410 ± 53
Blood neutrophil count (×109 /L)●●●
5.2 ± 0.5
6.0 ± 0.3
4.5 ± 0.9
6.5 ± 0.4
Bronchial histamine threshold (BHT)□
≤2.0 mg/mL
4
2
1
4.0 mg/mL
9
2
4
8.0 mg/mL
11
3
3
16.0 mg/mL
4
5
2
32.0 mg/mL
5
2
2
>32.0 mg/mL
6
1
0
Values: mean ± SD; ●: normal value = 4.0 − 10.0 × 109 /L; ●●: normal value ≤ 300 × 106/L; ●●●: normal value: 2.0−7.2 × 109/L; □: normal value ≥ 32.0 mg/mL.
