Induction of Specific Immunotherapy with Hymenoptera Venoms Using Ultrarush Regimen in Children: Safety and Tolerance

Table 3

Subjects with side effects.

Sex	Age (y)	Insect	Grade at sting	Side effects	Grade	At dose in μg	Therapy
F	8.1	Bee	II	Generalized urticaria, cough (no wheezing, no dyspnoea, no stridor)	II	50	Antihistamines, Corticosteroids i.v.
M	9.5	Bee	Sensit. (IV)	Dizziness	other	30	None
M	9.5	Bee	II-III	Generalyzed urticaria	I	30	Antihistamines i.v.
M	10.9	Bee	III	Urticaria, dyspnoea, wheezing	III	30	Antihistamines, Corticosteroids i.v., Salbutamol-inhalation
M	14.7	Bee	III	Generalized urticaria; dyspnoea, constriction in chest	IIII	2050	Antihistamines, Corticosteroids i.v.dito + inhal. of Adrenalin/Salbutamol
F	10.3	Bee	II-III	Urticaria about 3 h after last injection (50 𝜇g)	I	50	Antihistamines, Corticosteroids i.v.
F	10.4	Bee	II	Slight dyspnoea; fast, spontaneous normalization	III	1	None
M	12.1	Bee	III-IV	Generalized urticaria, itching in the throat	I	30	Antihistamines, Corticosteroids i.v
M	10.5	Bee	II-III	Itching in the throat	other	50	Cetirizin per os
F	8.7	Bee	III	Chest pain, inspiratory stridor, chest pain, in-and expiratory stridor	IIIIII	1050	Antihistamines, Corticosteroids i.v., Adrenalin-inhalation dito + Salbutamol-inhalation, Corticosteroids i.v. (before going home)
F	14.1	Bee	III	Slight periorbital swelling	II	1, 30 and 50	Antihistamines i.v. after 1ug
M	15.1	Bee	II	Itching in meatus acusticus, rash chest, several urticarial lesions on the left arm	I	50	None
F	15.0	Wasp	III	Dysphagia, passing dyspnea	III	0.1	Antihistamines and Corticosteroids i.v, and again before going home
F	11.3	Wasp	III	Slight prickle of the tongue	other	10	None
M	10.3	Bee	IV	Redness and one urticarial lesion on the left cheek	I	50	none, 1 Levocetirizine per os before going home
M	10.7	Wasp	III	Generalyzed urticaria	I	50	Levocetirizin per os
All children				Local redness and swelling, sometimes overheating and itching at the injection site. Therapy if needed: Coldpack and/or Antihistamin gel