Research Article

Reticular Basement Membrane Vessels Are Increased in COPD Bronchial Mucosa by Both Factor VIII and Collagen IV Immunostaining and Are Hyperpermeable

Figure 3

Bland and Altman plots for number of vessels and mean vascular size (MVS) in the reticular basement membrane (Rbm) and lamina propria (LP) in COPD subjects. Number of vessels is expressed as No/mm Rbm and No/mm² LP. MVS is presented as area μm²/No. For MVS in the LP, the agreement between the two methods was best when vessels were relatively smaller and the differences increased as MVS increased, with anti-Collagen IV showing larger MVS than anti-Factor VIII. Description of the measurements and abbreviations are presented in Figure 2.
958383.fig.003a
(a)
958383.fig.003b
(b)
958383.fig.003c
(c)
958383.fig.003d
(d)