Research Article

Increased Expression of RhoA in Epithelium and Smooth Muscle of Obese Mouse Models: Implications for Isoprenoid Control of Airway Smooth Muscle and Fibroblasts

Figure 2

RhoA expression is increased in obese mice. RhoA expression in mouse nasal epithelium and tracheal smooth muscle cells from wild-type (wt) and leptin-deficient (ob) mice. (a) Representative gel showing RhoA and actin expression from excised mouse nasal epithelium. (b) Relative density (RhoA/actin) quantification of RhoA protein content in nasal epithelium of wt and ob/ob mice. (c) Representative gel showing RhoA and active expression from mouse tracheal smooth muscle cells. (d) Relative density (RhoA/actin) quantification of RhoA content in tracheal cells from wt and ob/ob mice. Error bars represent SEM; . Number of replicates is shown in parentheses above each bar. Replicates represent individual mice.
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