Fluorine-Tagged 5-Hydroxytryptophan to Investigate Amino Acid Metabolism In Vivo

Figure 1

6-heptafluorobutyryl-5-hydroxytryptophan. 5-HTP tagged with a heptafluorobutyryl moiety (perfluorinated 5-hydroxytryptophan, PF-5-HTP). The active isomer of PF-5-HTP has a multiple-fluorine atom tag attached to the 6 position on the indole ring, away from the enzymatic activity.