Functionally Relevant Residues of Cdr1p: A Multidrug ABC Transporter of Human Pathogenic Candida albicans

Figure 2

Sequence logos of CaCdr1p transmembrane segment (TMSs) residues with other fungal PDR transporters. Each logo consists of stacks of symbols, one stack for each position in the sequence. The scale indicates the certainty of finding a particular amino acid at a given position and is determined by multiplying the frequency of that amino acid by the total information at that position. The residues at each position are arranged in order of predominance from top to bottom, with the highest frequency residue at the top. The height of symbols within the stack indicates the relative frequency of each amino acid at that position. Colors such as green defines polar, blue correspond to basic, red to acidic, black to hydrophobic, and violet represent the amino acids that have polar amide group.