Functionally Relevant Residues of Cdr1p: A Multidrug ABC Transporter of Human Pathogenic Candida albicans

Table 1

Substrates and inhibitors of CaCDR1 substrates.

Substrates	Fluconazole, ketoconazole, voriconazole, Itraconazole, miconazole, lipids, steroids, R6G, cycloheximide, rhodamine 123, cerulenin, trifluoperazine, nigericin, tamoxifen, verapamil, cycloheximide, propanil, diuron, linuron, disulfiram, anisomycin, doxorubicin, 4-nitroquinoline –N-oxide, benomyl, yohimbine HCl, quinidine, etoposide, chlorobromuron, vinblastine, tamoxifen, gefitinib, fluphenazine, topotecan, daunorubicin, DM-11, AT-12 niguldipine, dexamethasone, berberine, terbinafine, tritylmazole	[7, 53]
Inhibitors/modulators	Milbemycins, enniatin, FK506, FK520, unnarmicins, curcumin, disulfiram	[54–57]